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Epithelial-mesenchymal transition and H<sub>2</sub>O<sub>2</sub> signaling – a driver of disease progression and a vulnerability in cancers

15 Jan 2022

Abstract excerpt

Abstract Mutation-selective drugs constitute a great advancement in personalized anticancer treatment with increased quality of life and overall survival in cancers. However, the high adaptability and evasiveness of cancers can lead to disease progression and the development of drug resistance, which cause recurrence and metastasis. A common characteristic in advanced neoplastic cancers is the...

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PMID: 35032422
DOI: 10.1515/hsz-2021-0341

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