Article
Metabolic risk factors, genetic predisposition, and risk of severe liver disease in Chinese: a prospective study of 0.5 million people.
The American journal of clinical nutrition - 2 Aug 2021
Pang Yuanjie, Lv Jun, Kartsonaki Christiana, Yu Canqing, Guo Yu, Chen Yiping, Yang Ling, Millwood Iona Y, Walters Robin G, Wang Sisi, Chen Junshi, Chen Zhengming, Li Liming
Abstract excerpt
BACKGROUND: Metabolic risk factors have been shown to be associated with severe liver disease (SLD) in Chinese populations. However, there is limited evidence on the combined impact of these factors, or the genetic variants associated with SLD. OBJECTIVES: We examined the associations of combined metabolic risk factors with risks of SLD, both overall and by genetic predisposition to SLD. METHODS: The study...
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