Article
Gene polymorphism associated with FOXP3, CTLA-4 and susceptibility to pre-eclampsia: a meta-analysis and trial sequential analysis.
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology - 1 Jul 2022
Liu Jing, Song Guang, Zhao Ge, Meng Tao
Abstract excerpt
Previous studies have detected the correlation of polymorphisms in regulatory T cells associated genes FOXP3 and CTLA-4 with pre-eclampsia (PE) risk, but the results are inconsistent among studies. Eligible studies were retrieved in several database. Odds ratios (ORs) with 95% confidence intervals (CIs) were utilised to evaluate the relationship between FOXP3 rs3761548, FOXP3 rs2232365, CTLA-4 rs231775...
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