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Article

A patient with two gliomas with independent oligodendroglioma and glioblastoma biology proved by DNA-methylation profiling: a case report and review of the literature.

Brain tumor pathology - 1 Apr 2022

Kraus Theo F J, Schwartz Christoph, Machegger Lukas, Zellinger Barbara, Hölzl Dorothee, Schlicker Hans U, Pöppe Johannes, Ladisich Barbara, Spendel Mathias, Kral Michael, Sotlar Karl

Abstract excerpt

Here, we report on a patient presenting with two histopathologically distinct gliomas. At the age of 42, the patient underwent initial resection of a right temporal oligodendroglioma IDH mutated 1p/19q co-deleted WHO Grade II followed by adjuvant radiochemotherapy with temozolomide. 15 months after initial diagnosis, the patient showed right hemispheric tumor progression and an additional new left frontal...

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Identifiers

PMID: 35018523
DOI: 10.1007/s10014-021-00423-0
PMCID: PMC9090705

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