Article
Tumor cells with neuronal intermediate progenitor features define a subgroup of 1p/19q co-deleted anaplastic gliomas.
Brain pathology (Zurich, Switzerland) - 1 Sept 2017
Bielle Franck, Ducray François, Mokhtari Karima, Dehais Caroline, Adle-Biassette Homa, Carpentier Catherine, Chanut Anaïs, Polivka Marc, Poggioli Sylvie, Rosenberg Shai, Giry Marine, Marie Yannick, Duyckaerts Charles, Sanson Marc, Figarella-Branger Dominique, Idbaih Ahmed
Abstract excerpt
The integrated diagnosis of anaplastic oligodendroglioma, IDH mutant and 1p/19q co-deleted, grade III (O3id ) is a histomolecular entity that WHO 2016 classification distinguished from other diffuse gliomas by specific molecular alterations. In contrast, its cell portrait is less well known. The present study is focused on intertumor and intratumor, cell lineage-oriented, heterogeneity in O3id . Based on...
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