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Article

Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups.

Acta neuropathologica communications - 13 Jan 2016

Hinrichs Benjamin H, Newman Scott, Appin Christina L, Dunn William, Cooper Lee, Pauly Rini, Kowalski Jeanne, Rossi Michael R, Brat Daniel J

Abstract excerpt

INTRODUCTION: Glioblastoma with oligodendroglioma component (GBM-O) was recognized as a histologic pattern of glioblastoma (GBM) by the World Health Organization (WHO) in 2007 and is distinguished by the presence of oligodendroglioma-like differentiation. To better understand the genetic underpinnings of this morphologic entity, we performed a genome-wide, integrated copy number, mutational and transcriptomic...

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Source

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Identifiers

PMID: 26757882
DOI: 10.1186/s40478-015-0270-7
PMCID: PMC4711079

Genes

IDH1
EGFR
PDGFRA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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