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Article

Structural insights in cell-type specific evolution of intra-host diversity by SARS-CoV-2.

Nature communications - 11 Jan 2022

Gupta Kapil, Toelzer Christine, Williamson Maia Kavanagh, Shoemark Deborah K, Oliveira A Sofia F, Matthews David A, Almuqrin Abdulaziz, Staufer Oskar, Yadav Sathish K N, Borucu Ufuk, Garzoni Frederic, Fitzgerald Daniel, Spatz Joachim, Mulholland Adrian J, Davidson Andrew D, Schaffitzel Christiane, Berger Imre

Abstract excerpt

As the global burden of SARS-CoV-2 infections escalates, so does the evolution of viral variants with increased transmissibility and pathology. In addition to this entrenched diversity, RNA viruses can also display genetic diversity within single infected hosts with co-existing viral variants evolving differently in distinct cell types. The BriSΔ variant, originally identified as a viral subpopulation from...

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Identifiers

PMID: 35017512
DOI: 10.1038/s41467-021-27881-6
PMCID: PMC8752678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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