Article

Structural flexibility of the SARS-CoV-2 genome relevant to variation, replication, pathogenicity, and immune evasion

2021-12-21

Abstract excerpt

The SARS-CoV-2 pandemic continues to be driven by viral variants. Most research has focused on structural proteins and on site-specific mutations. Here, we describe recombination events involving genomic terminal sequences in SARS-CoV-2 and related viruses leading to structural rearrangements in terminal and coding regions and discuss their potential contributions to viral variation, replication, pathogenicity, an...

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Literature Corpus work: d4b5eea1-f9ca-5511-8a43-0a360619dea5
DOI: 10.1101/2021.12.20.473542

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