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Article

Molecular Aspects of Viral Pathogenesis in Emerging SARS-CoV-2 Variants: Evolving Mechanisms of Infection and Host Response.

International journal of molecular sciences - 15 Jan 2026

Muntean Sofia Teodora, Cozac-Szoke Andreea-Raluca, Tinca Andreea Cătălina, Kosovski Irina Bianca, Vultur Silviu, Vultur Mara, Cotoi Ovidiu Simion, Sin Anca Ileana

Abstract excerpt

Although the SARS-CoV-2 pandemic no longer poses a global emergency, the virus continues to diversify and acquire immunoevasive properties. Understanding the molecular pathways that shape SARS-CoV-2 pathogenesis has become essential. In this paper, we summarize the most recent current evidence on how the spike protein structurally evolves, on changes in key non-structural proteins, such as nsp14, and on host...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41596537
DOI: 10.3390/ijms27020891
PMCID: PMC12841273

Genes

TMPRSS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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