Article
No evidence that genetic predictors of susceptibility predict changes in core outcomes in JIA.
Rheumatology (Oxford, England) - 6 Oct 2022
Yarwood Annie, Shoop-Worrall Stephanie, López-Isac Elena, Smith Samantha Louise, Morris Andrew P, Bowes John David, Tordoff Melissa, Hyrich Kimme L, Thomson Wendy, Eyre Stephen
Abstract excerpt
OBJECTIVES: The clinical progression of JIA is unpredictable. Knowing who will develop severe disease could facilitate rapid intensification of therapies. We use genetic variants conferring susceptibility to JIA to predict disease outcome measures. METHODS: A total of 713 JIA patients with genotype data and core outcome variables (COVs) at diagnosis (baseline) and 1 year follow-up were identified from the...
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