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Article

Unique Molecular Signatures Are Associated with Aggressive Histology in Pediatric Differentiated Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association - 1 Mar 2022

Mollen Kevin P, Shaffer Amber D, Yip Linwah, Monaco Sara E, Huyett Phillip, Viswanathan Pushpa, Witchel Selma F, Duvvuri Umamaheswar, Simons Jeffrey P

Abstract excerpt

Background: Molecular testing (MT) enhances the diagnostic accuracy of thyroid fine-needle aspiration biopsy, reducing the need for diagnostic lobectomy in adult patients with indeterminate nodules (Bethesda class III/IV). However, little is known about genetic alterations in pediatric thyroid carcinoma (TC). Our aim was to analyze MT results of pediatric differentiated TC (DTC) cases to determine associations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34915753
DOI: 10.1089/thy.2021.0317

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