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Article

Selective influence of rat genotype on age-related regional changes in forebrain muscarinic binding.

Neurobiology of aging - 1 Jan 2000

Gilad G M, Rabey J M, Shenkman L, Gilad V H

Abstract excerpt

Muscarinic binding was analyzed in the hippocampus and frontal cerebral cortex of 3 (young) and 24-month-old (aged) inbred Wistar-Kyoto (WKY), Brown-Norway (BN) and Lewis rats, by the specific binding of the antagonist quinuclidinylbenzilate (QNB). While no age-related changes were detected in the hippocampus of all strains, complex changes were found in the cortex. Maximal binding capacity (Bmax) of [3H]QNB was...

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PMID: 3501549
DOI: 10.1016/0197-4580(87)90126-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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