Article
Effects of genotype on age-related alterations in the concentrations of stress hormones in plasma and hypothalamic monoamines in rats.
Journal of reproduction and fertility. Supplement - 1 Jan 1993
Gilad G M, Li R, Wyatt R J, Tizabi Y
Abstract excerpt
The adaptive response of the neuroendocrine system to stress is known to be impaired during ageing, and this impairment may be genetically determined. To elucidate further the effect of genotype, inbred male rats of the Wistar-Kyoto (WKY) strain, characterized by their hyper-reactivity to stressors and shorter life span, were compared with Brown-Norway (BN) rats. In young BN rats, resting prolactin concentrations...
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