Article
[The effect of deprenil on the dopaminergic system of the brain in mice of different genotypes during aging].
Zhurnal vysshei nervnoi deiatelnosti imeni I P Pavlova - 1 Jan 2000
Skrinskaia Iu A, Nikulina E M
Abstract excerpt
Effects of aging on brain dopaminergic system, e.g., neurotransmitter metabolism and different kinds of dopamine-dependent behaviour, were studied in mice of three inbred strains. Homovanillic acid concentrations in structures of both nigrostriatal (striatum) and mesolimbic (n. accumbens with tuberculum olfactorium) systems were found to be increased in the aged animals. Aged mice of the strains studied were...
Topics
- Aging
- Animals
- Behavior, Animal
- Brain
- Genotype
- Male
- Mice
- Mice, Inbred A
- Mice, Inbred C3H
- Mice, Inbred C57BL
- Receptors, Dopamine
- Selegiline
