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Article

A robust and miniaturized screening platform to study natural products affecting metabolism and survival in Caenorhabditis elegans.

Scientific reports - 23 Jul 2020

Zwirchmayr Julia, Kirchweger Benjamin, Lehner Theresa, Tahir Ammar, Pretsch Dagmar, Rollinger Judith M

Abstract excerpt

In this study a robust, whole organism screening based on Caenorhabditis elegans is presented for the discovery of natural products (NP) with beneficial effects against obesity and age-related diseases. Several parameters of the elaborated workflow were optimized to be adapted for probing multicomponent mixtures combining knowledge from traditional medicine and NP chemistry by generating optimized small-scale...

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Identifiers

PMID: 32704017
DOI: 10.1038/s41598-020-69186-6
PMCID: PMC7378205

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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