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Article

The Role of LIM Kinase in the Male Urogenital System

28 Dec 2021

Abstract excerpt

The LIM kinases (LIMK1 and LIMK2), known as downstream effectors, and the Rho-associated protein kinase (ROCK), a regulator of actin dynamics, have effects on a diverse set of cellular functions. The LIM kinases are involved in the function of the male urogenital system by smooth muscle contraction via phosphorylation of cofilin and subsequent actin cytoskeleton reorganization. Although LIMK1 and LIMK2 share...

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Identifiers

PMID: 35011645
DOI: 10.3390/cells11010078

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Related research

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The Role of LIM Kinase in the Male Urogenital SystemPMID 35011645Read ↗

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Specific activation of LIM kinase 2 via phosphorylation of threonine 505 by ROCK, a Rho-dependent protein kinase.Semantic proximity Read ↗

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