Article
Molecular analysis of endometrial serous carcinoma reveals distinct clinicopathologic and genomic subgroups.
Gynecologic oncology - 1 Mar 2022
Lin Douglas I, Fine Alexander, Danziger Natalie A, Huang Richard S P, Mata Douglas A, Decker Brennan, Killian Jonathan K, Ramkissoon Shakti H, Lechpammer Mirna, Janovitz Tyler, Ross Jeffrey S, Sokol Ethan S, Elvin Julia A
Abstract excerpt
OBJECTIVES: Endometrial serous carcinoma (EMSC) is an aggressive variant of uterine cancer with limited therapeutic options. We sought to define distinct clinicopathologic and genomic EMSC subgroups. METHODS: We retrospectively analyzed 2159 EMSC and 2346 endometrioid-type endometrial carcinomas (EEC) tissue specimens that had undergone comprehensive genomic profiling (CGP) via the FoundationOne CDx assay during...
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