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Article

CRISPRi links COVID-19 GWAS loci to LZTFL1 and RAVER1.

EBioMedicine - 1 Jan 2022

Fink-Baldauf Iris M, Stuart William D, Brewington John J, Guo Minzhe, Maeda Yutaka

Abstract excerpt

BACKGROUND: To identify host genetic variants (SNPs) associated with COVID-19 disease severity, a number of genome-wide association studies (GWAS) have been conducted. Since most of the identified variants are located at non-coding regions, such variants are presumed to affect the expression of neighbouring genes, thereby influencing COVID-19 disease severity. However, it remains largely unknown which genes are...

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Identifiers

PMID: 34998241
DOI: 10.1016/j.ebiom.2021.103806
PMCID: PMC8731227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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