Article
The ALA5/ALA6/ALA7 repeat polymorphisms of the glutathione peroxidase-1 (GPx1) gene and autism spectrum disorder.
Autism research : official journal of the International Society for Autism Research - 1 Feb 2022
Carducci Federica, Ardiccioni Chiara, Fiorini Rosamaria, Vignini Arianna, Di Paolo Alice, Alia Sonila, Barucca Marco, Biscotti Maria Assunta
Abstract excerpt
Autism is a severe neurodevelopmental disorder leading to deficits in social interaction, communication, and several activities. An increasing number of evidence suggests a role of oxidative stress in the etiology of autism spectrum disorder (ASD). Indeed, impaired antioxidant mechanisms may lead to the inadequate removal of H2 O2 with a consequent increase in highly active hydroxyl radicals and other reactive...
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