Article
Genetic variant of glutathione peroxidase 1 in autism.
Brain & development - 1 Feb 2010
Ming Xue, Johnson William G, Stenroos Edward S, Mars Audrey, Lambert George H, Buyske Steven
Abstract excerpt
Genetic factors can contribute to autistic disorder (AD). Abnormal genes of oxidative stress pathways and increased oxidative stress have been reported in autism spectrum disorders. Polymorphisms of genes involved in glutathione metabolism, e.g. GSTP1 and GSTM1 are reportedly associated with autistic disorder. We investigated a GCG repeat polymorphism of a human glutathione peroxidase (GPX1) polyalanine repeat...
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