Article
Cerebrospinal fluid as a medium of liquid biopsy in the management of patients with non-small-cell lung cancer having central nervous system metastasis.
Frontiers in bioscience (Landmark edition) - 30 Dec 2021
Chiang Chi-Lu, Huang Hsu-Ching, Luo Yung-Hung, Chiu Chao-Hua
Abstract excerpt
The molecular profiling of tumors is fundamental in the management of advanced non-small-cell lung cancer (NSCLC). A tissue specimen obtained from biopsy is needed for diagnosis and mutation analysis. However, this may not be feasible for some metastatic sites, such as central nervous system (CNS) lesions, particularly for repeated biopsy. Liquid biopsy with plasma is an emerging tool for molecular testing and...
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