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The Use of Liquid Biopsy in the Molecular Analysis of Plasma Compared to the Tumour Tissue from a Patient with Brain Metastasis: A Case Report.

Medicina (Kaunas, Lithuania) - 25 Feb 2023

Aran Veronica, Zogbi Vinicius Mansur, Miranda Renan Lyra, Andreiuolo Felipe, Silva Canedo Nathalie Henriques, Nazaré Carolina Victor, Niemeyer Filho Paulo, Neto Vivaldo Moura

Abstract excerpt

Different cancers have multiple genetic mutations, which vary depending on the affected tumour tissue. Small biopsies may not always represent all the genetic landscape of the tumour. To improve the chances of identifying mutations at different disease stages (early, during the disease course, and refractory stage), liquid biopsies offer an advantage to traditional tissue biopsy. In addition, it is possible to...

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PMID: 36984460
DOI: 10.3390/medicina59030459
PMCID: PMC10055748

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