Article
Mutational landscape of paired primary and synchronous metastatic lymph node in chemotherapy naive gallbladder cancer.
Molecular biology reports - 1 Feb 2022
Fan Boqiang, Xu Xianfeng, Wang Xuehao
Abstract excerpt
BACKGROUND: Comprehensive genomic analysis of paired primary tumors and their metastatic lesions may provide new insights into the biology of metastatic processes and therefore guide the development of novel strategies for intervention. To date, our knowledge of the genetic divergence and phylogenetic relationships in gallbladder cancer (GBC) is limited. METHODS: We performed whole exome sequencing for 5 patients...
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