Article
Side effects after docetaxel treatment in Taiwanese breast cancer patients with CYP3A4, CYP3A5, and ABCB1 gene polymorphisms.
Clinica chimica acta; international journal of clinical chemistry - 27 Jun 2009
Tsai Shih-Meng, Lin Chiou-Ya, Wu Szu-Hsien, Hou Linda Ann, Ma Hsu, Tsai Li-Yu, Hou Ming-Feng
Abstract excerpt
BACKGROUND: Breast cancer patients initiating TEC (including docetaxel, epirubicin, and cyclophosphamide) treatment were genotyped for CYP3A4, CYP3A5, and ABCB1 to identify variability factors of side effects for docetaxel. METHODS: The planned dose of docetaxel per course was formulated according to each patient's height and weight. Each participant had received TEC treatment for 6 consecutive cycles. The single...
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