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Article

Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel-induced leukopenia.

Cancer science - 1 May 2008

Kiyotani Kazuma, Mushiroda Taisei, Kubo Michiaki, Zembutsu Hitoshi, Sugiyama Yuichi, Nakamura Yusuke

Abstract excerpt

Despite long-term clinical experience with docetaxel, unpredictable severe adverse reactions remain an important determinant for limiting the use of the drug. To identify a genetic factor(s) determining the risk of docetaxel-induced leukopenia/neutropenia, we selected subjects who received docetaxel chemotherapy from samples recruited at BioBank Japan, and conducted a case-control association study. We genotyped...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 18294295
DOI: 10.1111/j.1349-7006.2008.00765.x
PMCID: PMC11159748

Genes

ABCC2
ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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