The Brain-Derived Neurotrophic Factor Functional Polymorphism and Hand Grip Strength Impact the Association between Brain-Derived Neurotrophic Factor Levels and Cognition in Older Adults in the United States.

doi:10.1177/10998004211065151

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The Brain-Derived Neurotrophic Factor Functional Polymorphism and Hand Grip Strength Impact the Association between Brain-Derived Neurotrophic Factor Levels and Cognition in Older Adults in the United States.

Biological research for nursing - 1 Apr 2022

Liu Tingting, Li Hongjin, Conley Yvette P, Primack Brian A, Wang Jing, Li Changwei

Abstract excerpt

INTRODUCTION: Aging is associated with subtle cognitive decline in attention, memory, executive function, processing speed, and reasoning. Although lower brain-derived neurotrophic factor (BDNF) has been linked to cognitive decline among older adults, it is not known if the association differs among individuals with various BDNF Val66Met (rs6265) genotypes. In addition, it is not clear whether these associations...

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PMID: 34974714
DOI: 10.1177/10998004211065151

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