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Article

Aerobic exercise improves executive functions in females, but not males, without the BDNF Val66Met polymorphism.

Biology of sex differences - 3 Apr 2023

Barha Cindy K, Starkey Samantha Y, Hsiung G Y Robin, Tam Roger, Liu-Ambrose Teresa

Abstract excerpt

BACKGROUND: Aerobic exercise promotes cognitive function in older adults; however, variability exists in the degree of benefit. The brain-derived neurotropic factor (BDNF) Val66Met polymorphism and biological sex are biological factors that have been proposed as important modifiers of exercise efficacy. Therefore, we assessed whether the effect of aerobic exercise on executive functions was dependent on the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37013586
DOI: 10.1186/s13293-023-00499-7
PMCID: PMC10069071

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