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Article

New insights of falcipain 2 structure from Plasmodium falciparum 3D7 strain.

Biochemical and biophysical research communications - 29 Jan 2022

Chakraborty Subhoja, Alam Benazir, Biswas Sampa

Abstract excerpt

Malaria identifies as a tropical hallmark, conforming to the burgeoning notion of escalating drug resistance among virulent strains, with the burdensome Plasmodium falciparum under its wing. The cysteine protease Falcipain-2 (FP2) is released in the parasite's food vacuole in the trophozoite stage and contributes to disease progression through its hemoglobinase activity. In the present study, we have determined...

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PMID: 34974303
DOI: 10.1016/j.bbrc.2021.12.080

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