Article
Monitoring B cell alloresponses in rats.
Journal of immunological methods - 1 Feb 2022
Steines Louisa, Scharf Mona, Hoffmann Petra, Schuster Antonia, Banas Bernhard, Bergler Tobias
Abstract excerpt
Antibody-mediated rejection is a major cause of graft failure in organ transplantation. For this reason, B cell responses are of particular interest to transplantation research. Rats are important model organisms for transplant studies, but B cell alloimmune assays and B cell subset markers are poorly established in rats. We alloimmunized rats by donor blood injection using the high responder rat strain...
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