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Article

Large-scale analysis of BAP1 expression reveals novel associations with clinical and molecular features of malignant pleural mesothelioma.

The Journal of pathology - 1 Jan 2021

De Rienzo Assunta, Chirieac Lucian R, Hung Yin P, Severson David T, Freyaldenhoven Samuel, Gustafson Corinne E, Dao Nhien T, Meyerovitz Claire V, Oster Michela E, Jensen Roderick V, Yeap Beow Y, Bueno Raphael, Richards William G

Abstract excerpt

BRCA1-associated protein-1 (BAP1) expression is commonly lost in several tumors including malignant pleural mesothelioma (MPM). Presence or absence of immunohistochemical BAP1 nuclear staining in tumor cells is currently used for differential diagnosis of MPM. In this study, a large cohort of 596 MPM tumors with available clinical data was analyzed to examine associations of BAP1 staining pattern with clinical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial-Mesenchymal Transition

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Identifiers

PMID: 32944962
DOI: 10.1002/path.5551
PMCID: PMC7756745

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