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Article

The role of ubiquitin-specific peptidases in glioma progression

27 Dec 2021

Abstract excerpt

The balance between ubiquitination and deubiquitination is crucial for protein stability, function and location under physiological conditions. Dysregulation of E1/E2/E3 ligases or deubiquitinases (DUBs) results in malfunction of the ubiquitin system and is involved in many diseases. Increasing reports have indicated that ubiquitin-specific peptidases (USPs) play a part in the progression of many kinds of cancers...

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PMID: 34968923
DOI: 10.1016/j.biopha.2021.112585

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