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Article

USP18 regulates the malignant phenotypes of glioblastoma stem cells.

Pathology, research and practice - 1 Jul 2023

Li Lingfei, Yin Yuxin, Zhang Jinping, Wu Xiaoxu, Liu Jin, Chai Jia, Yang Yanru, Li Mingyang, Jia Qingge, Liu Yixiong

Abstract excerpt

Glioblastoma (GBM) is the most malignant primary brain tumor. The 5-year survival rate of the patients is poor, and they are prone to relapse and the treatment is limited. Therefore, the search for biological targets is one of the key measures for the treatment and prognosis of GBM. Ubiquitin-specific peptidase 18 (USP18) plays a regulatory role in tumorigenesis. In this study, we found that USP18 was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 37257245
DOI: 10.1016/j.prp.2023.154572

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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