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Article

Dichotomous Responses to Chronic Fetal Hypoxia Lead to a Predetermined Aging Phenotype.

Molecular & cellular proteomics : MCP - 1 Feb 2022

Rudloff Stefan, Bileck Andrea, Janker Lukas, Wanner Nicola, Liaukouskaya Nastassia, Lundby Carsten, Huber Tobias B, Gerner Christopher, Huynh-Do Uyen

Abstract excerpt

Hypoxia-induced intrauterine growth restriction increases the risk for cardiovascular, renal, and other chronic diseases in adults, representing thus a major public health problem. Still, not much is known about the fetal mechanisms that predispose these individuals to disease. Using a previously validated mouse model of fetal hypoxia and bottom-up proteomics, we characterize the response of the fetal kidney to...

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Identifiers

PMID: 34958949
DOI: 10.1016/j.mcpro.2021.100190
PMCID: PMC8808178

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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