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Obesity increases heart failure incidence and mortality: observational and Mendelian randomization studies totalling over 1 million individuals

21 Dec 2021

Abstract excerpt

AIMS: Whether high body mass index (BMI) causally influences development and prognosis of heart failure has implications for clinical practice. We tested the hypotheses that high BMI causally influences heart failure incidence and mortality. METHODS AND RESULTS: Using observational and Mendelian randomization causal, genetic analyses, we studied 106 121 individuals from the Copenhagen General Population Study, 18...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34954789
DOI: 10.1093/cvr/cvab368

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