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Article

Structure and function of ABCA4 and its role in the visual cycle and Stargardt macular degeneration.

Progress in retinal and eye research - 1 Jul 2022

Molday Robert S, Garces Fabian A, Scortecci Jessica Fernandes, Molday Laurie L

Abstract excerpt

ABCA4 is a member of the superfamily of ATP-binding cassette (ABC) transporters that is preferentially localized along the rim region of rod and cone photoreceptor outer segment disc membranes. It uses the energy from ATP binding and hydrolysis to transport N-retinylidene-phosphatidylethanolamine (N-Ret-PE), the Schiff base adduct of retinal and phosphatidylethanolamine, from the lumen to the cytoplasmic leaflet...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 34954332
DOI: 10.1016/j.preteyeres.2021.101036

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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