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Article

The ATP-binding cassette transporter ABCA4: structural and functional properties and role in retinal disease.

Advances in experimental medicine and biology - 1 Jan 2010

Tsybovsky Yaroslav, Molday Robert S, Palczewski Krzysztof

Abstract excerpt

ATP-binding cassette transporters (ABC transporters) utilize the energy of ATP hydrolysis to translocate an unusually diverse set of substrates across cellular membranes. ABCA4, also known as ABCR, is a approximately 250 kDa single-chain ABC transporter localized to the disk margins of vertebrate photoreceptor outer segments. It is composed of two symmetrically organized halves, each comprising six...

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Source

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Identifiers

PMID: 20711710
DOI: 10.1007/978-1-4419-5635-4_8
PMCID: PMC2930353

Genes

ABCA4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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