ATP-binding cassette transporter ABCA4: molecular properties and role in vision and macular degeneration.

doi:10.1007/s10863-007-9118-6

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Article

ATP-binding cassette transporter ABCA4: molecular properties and role in vision and macular degeneration.

Journal of bioenergetics and biomembranes - 1 Dec 2007

Molday Robert S

Abstract excerpt

ABCA4, also known as ABCR or the rim protein, is a member of the ABCA subfamily of ATP binding cassette (ABC) transporters expressed in vertebrate rod and cone photoreceptor cells and localized to outer segment disk membranes. ABCA4 is organized in two tandem halves, each consisting of a transmembrane segment followed successively by a large exocytoplasmic domain, a multispanning membrane domain, and a...

Topics

ATP-Binding Cassette Transporters
Animals
Humans
Macular Degeneration
Mutation
Vision, Ocular

Source

Open in PubMed

Identifiers

PMID: 17994272
DOI: 10.1007/s10863-007-9118-6

Genes

ABCA4
RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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