Article
Letter to the Editor: on the stability and internal consistency of component-wise sparse mixture regression-based clustering.
Briefings in bioinformatics - 17 Jan 2022
Zhang Bo, He Jianghua, Hu Jinxiang, Koestler Devin C, Chalise Prabhakar
Abstract excerpt
Understanding the relationship between molecular markers and a phenotype of interest is often obfuscated by patient-level heterogeneity. To address this challenge, Chang et al. recently published a novel method called Component-wise Sparse Mixture Regression (CSMR), a regression-based clustering method that promises to detect heterogeneous relationships between molecular markers and a phenotype of interest under...
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