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Comprehensive Analysis of the Expression and Prognosis Value of Claudin Family Members in Clear Cell Renal Cell Carcinoma

2022-04-13

Abstract excerpt

<h4>Background: </h4> Clear cell renal cell carcinoma (ccRCC) accounts for 80% of all renal cancers and has a poor prognosis. The claudin (CLND) family comprises a group of transmembrane proteins associated with tight junctions (TJs). Studies have found that the abnormal expression of CLNDs can influence TJ-function and plays an important role in the occurrence, development, and metastasis of malignant tumors in a...

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Literature Corpus work
b3096368-4cba-54b1-a2f3-a2ddee63235e
DOI
10.21203/rs.3.rs-1520786/v1
Open publication

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