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TNFA and IL10 Polymorphisms and IL-6 and IL-10 Levels Influence Disease Severity in Influenza A(H1N1)pdm09 Virus Infected Patients.

Genes - 28 Nov 2021

Alagarasu Kalichamy, Kaushal Himanshu, Shinde Pooja, Kakade Mahadeo, Chaudhary Urmila, Padbidri Vikram, Sangle Shashikala A, Salvi Sonali, Bavdekar Ashish R, D'costa Pradeep, Choudhary Manohar Lal

Abstract excerpt

Cytokines are key modulators of immune response, and dysregulated production of proinflammatory and anti-inflammatory cytokines contributes to the pathogenesis of influenza A(H1N1)pdm09 virus infection. Cytokine production is impacted by single nucleotide polymorphisms (SNPs) in the genes coding for them. In the present study, SNPs in the IL6, TNFA, IFNG, IL17A, IL10, and TGFB were investigated for their...

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Identifiers

PMID: 34946862
DOI: 10.3390/genes12121914
PMCID: PMC8700762

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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