Article
Pandemic influenza A/H1N1 virus infection and TNF, LTA, IL1B, IL6, IL8, and CCL polymorphisms in Mexican population: a case-control study.
BMC infectious diseases - 13 Nov 2012
Morales-García Guadalupe, Falfán-Valencia Ramcés, García-Ramírez Román Alejandro, Camarena Ángel, Ramirez-Venegas Alejandra, Castillejos-López Manuel, Pérez-Rodríguez Martha, González-Bonilla César, Grajales-Muñíz Concepción, Borja-Aburto Víctor, Mejía-Aranguré Juan Manuel
Abstract excerpt
BACKGROUND: Some patients have a greater response to viral infection than do others having a similar level of viral replication. Hypercytokinemia is the principal immunopathological mechanism that contributes to a severer clinical course in cases of influenza A/H1N1. The benefit produced, or damage caused, by these cytokines in severe disease is not known. The genes that code for these molecules are polymorphic...
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