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Article

Genetic variants in IL1A and IL1B contribute to the susceptibility to 2009 pandemic H1N1 influenza A virus.

BMC immunology - 8 Aug 2013

Liu Yingxia, Li Shaoyuan, Zhang Guoliang, Nie Guang, Meng Zhizhong, Mao Dongting, Chen Chang, Chen Xinchun, Zhou Boping, Zeng Gucheng

Abstract excerpt

BACKGROUND: Host genetic variations may contribute to disease susceptibility of influenza. IL-1A and IL-1B are important inflammatory cytokines that mediate the inflammation and initiate the immune response against virus infection. In this study, we investigated the relationship between single-nucleotide polymorphisms (SNPs) of Interleukin-1A (IL-1A) and Interleukin-1B (IL-1B) and the susceptibility to 2009...

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Identifiers

PMID: 23927441
DOI: 10.1186/1471-2172-14-37
PMCID: PMC3750637

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