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Nuclear Sirtuins and the Aging of the Immune System

23 Nov 2021

Abstract excerpt

The immune system undergoes major changes with age that result in altered immune populations, persistent inflammation, and a reduced ability to mount effective immune responses against pathogens and cancer cells. Aging-associated changes in the immune system are connected to other age-related diseases, suggesting that immune system rejuvenation may provide a feasible route to improving overall health in the...

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PMID: 34946805
DOI: 10.3390/genes12121856

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