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Article

Abnormal Epigenetic Regulation of Immune System during Aging

12 Feb 2018

Abstract excerpt

Epigenetics refers to the study of mechanisms controlling the chromatin structure, which has fundamental role in the regulation of gene expression and genome stability. Epigenetic marks, such as DNA methylation and histone modifications, are established during embryonic development and epigenetic profiles are stably inherited during mitosis, ensuring cell differentiation and fate. Under the effect of intrinsic...

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PMID: 29483913
DOI: 10.3389/fimmu.2018.00197

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