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Mitochondrial Quality Control in Health and Disease

1 Aug 2025

Abstract excerpt

Mitochondria are central regulators of cellular energy metabolism, and their functional integrity is essential for maintaining cellular homeostasis. Mitochondrial quality control (MQC) encompasses a coordinated network of mitochondrial biogenesis, dynamics (fusion and fission), and selective autophagy (mitophagy), which together sustain mitochondrial structure and function. Under physiological conditions, MQC...

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PMID: 40821693
DOI: 10.1002/mco2.70319

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