Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yearlong COVID-19 Infection Reveals Within-Host Evolution of SARS-CoV-2 in a Patient With B-Cell Depletion

21 Dec 2021

Abstract excerpt

B-cell-depleting therapies may lead to prolonged disease and viral shedding in individuals infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and this viral persistence raises concern for viral evolution. We report sequencing of early and late samples from a 335-day infection in an immunocompromised patient. The virus accumulated a unique deletion in the amino-terminal domain of the spike...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19 Clinical Research Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to vaccines and immunoinformatics approaches

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 34940844
DOI: 10.1093/infdis/jiab622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yearlong COVID-19 Infection Reveals Within-Host Evolution of SARS-CoV-2 in a Patient With B-Cell DepletionPMID 34940844Read ↗

Year-long COVID-19 infection reveals within-host evolution of SARS-CoV-2 in a patient with B cell depletionSemantic proximity Read ↗

Emergence of multiple SARS-CoV-2 mutations in an immunocompromised hostSemantic proximity Read ↗

SARS-CoV-2 shedding, infectivity and evolution in an immunocompromised adult patientSemantic proximity Read ↗

Intra-host viral populations of SARS-CoV-2 in immunosuppressed patients with hematologic cancersSemantic proximity Read ↗

A highly divergent SARS-CoV-2 lineage B.1.1 sample in a patient with long-term COVID-19Semantic proximity Read ↗

A highly divergent SARS-CoV-2 lineage B.1.1 sample in a patient with long-term COVID-19Semantic proximity Read ↗

SARS-CoV-2 shedding and evolution in immunocompromised hosts during the Omicron period: a multicenter prospective analysisSemantic proximity Read ↗

Intra-host evolution provides for continuous emergence of SARS-CoV-2 variantsSemantic proximity Read ↗

Intra-Host Evolution Analyses in an Immunosuppressed Patient Supports SARS-CoV-2 Viral Reservoir Hypothesis.Semantic proximity Read ↗

SARS-CoV-2 evolution during prolonged infection in immunocompromised patientsSemantic proximity Read ↗

Intra-Host Evolution Provides for the Continuous Emergence of SARS-CoV-2 Variants.Semantic proximity Read ↗

SARS-CoV-2 in an immunocompromised host: convalescent plasma therapy and viral evolution elucidated by whole genome sequencing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.