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Article

The association of complex genetic background with the prognosis of acute leukemia with ambiguous lineage.

Scientific reports - 21 Dec 2021

Huang Jin, Zhou Jing, Xiao Min, Mao Xia, Zhu Li, Liu Songya, Li Qinlu, Wang Jin, Zhou Jianfeng, Cai Haodong, Wang Gaoxiang

Abstract excerpt

Acute leukemia with ambiguous lineage (ALAL) is a rare and highly aggressive malignancy with limited molecular characterization and therapeutic recommendations. In this study, we retrospectively analyzed 1635 acute leukemia cases in our center from January 2012 to June 2018. The diagnose of ALAL was based on either EGIL or 2016 WHO criteria, a total of 39 patients were included. Four patients diagnosed as acute...

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Identifiers

PMID: 34934076
DOI: 10.1038/s41598-021-03709-7
PMCID: PMC8692450

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