Article
Deciphering the Irregular Risk of Stroke Increased by Obesity Classes: A Stratified Mendelian Randomization Study.
Frontiers in endocrinology - 1 Jan 2021
Zou Xuelun, Wang Leiyun, Xiao Linxiao, Xu Zihao, Yao Tianxing, Shen Minxue, Zeng Yi, Zhang Le
Abstract excerpt
Background: To investigate the relationship between different classes of obesity and stroke, we conducted a stratified Mendelian randomization (MR) study. Methods: The body mass index (BMI) data of 263,407 Europeans with three classes of obesity (obesity class I, 30 kg/m2 ≤ BMI < 35 kg/m2; obesity class II, 35 kg/m2 ≤ BMI < 40 kg/m2; obesity class III, 40 kg/m2 ≤ BMI) were extracted from the Genetic Investigation...
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