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Article

Effect of genetic liability to visceral adiposity on stroke and its subtypes: A Mendelian randomization study.

International journal of stroke : official journal of the International Stroke Society - 1 Feb 2022

Yan Bin, Yang Jian, Qian Li, Gao Fengjie, Bai Ling, Wang Gang, Ma Xiancang

Abstract excerpt

BACKGROUND: Observational studies have found an association between visceral adiposity and stroke. AIMS: The purpose of this study was to investigate the role and genetic effect of visceral adipose tissue accumulation on stroke and its subtypes. METHODS: In this two-sample Mendelian randomization study, genetic variants (221 single nucleotide polymorphisms; P < 5 × 10-8) using as instrumental variables for...

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PMID: 33724079
DOI: 10.1177/17474930211006285

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