Article
Disentangling the genetic overlap between ischemic stroke and obesity
30 Dec 2024
Abstract excerpt
OBJECTIVE: Obesity has been recognized as a risk factor for cerebrovascular diseases, with observational studies suggesting a heightened incidence of stroke. However, the genetic epidemiology field has yet to reach a consensus on the causal relationship and genetic overlap between ischemic stroke (IS) and obesity. METHODS: We utilized linkage disequilibrium score regression, high-definition likelihood, and local...
